Publications

Testing and Assay Development

Sensitivity and specificity of a new automated system for the detection of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus nucleic acid in blood and plasma donations

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Frequent detection of the parvoviruses, PARV4 and PARV5, in plasma from blood donors and symptomatic individuals

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First report of human immunodeficiency virus transmission via an RNA-screened blood donation

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A novel Escherichia coli lipoprotein expression vector

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Candida albicans biofilm chip (CaBChip) for high-throughput antifungal drug screening

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High-throughput nano-biofilm microarray for antifungal drug discovery

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High-throughput screening of a collection of known pharmacologically active small compounds for identification of Candida albicans biofilm inhibitors

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Screening a Commercial Library of Pharmacologically Active Small Molecules against Staphylococcus aureus Biofilms

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Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi

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Antimicrobial and Antibiofilm Activity of Synergistic Combinations of a Commercially Available Small Compound Library With Colistin Against Pseudomonas aeruginosa

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High-throughput microarray for antimicrobial susceptibility testing

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Cellular and Molecular Biology

Temporal and spatial expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases following myocardial infarction

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Cardiac wound healing post-myocardial infarction: a novel method to target extracellular matrix remodeling in the left ventricle

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Extracellular matrix turnover and signaling during cardiac remodeling following MI: causes and consequences

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SPARC mediates early extracellular matrix remodeling following myocardial infarction

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In vivo matrix metalloproteinase-7 substrates identified in the left ventricle post-myocardial infarction using proteomics

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Tumor necrosis factor-alpha–converting enzyme roles in hypertension-induced hypertrophy: look both ways when crossing the street

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Stem cell mechanisms during left ventricular remodeling post-myocardial infarction: Repair and regeneration

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C-terminal fragment of transforming growth factor beta-induced protein (TGFBIp) is required for apoptosis in human osteosarcoma cells

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A Novel Collagen Matricryptin Reduces Left Ventricular Dilation Post-Myocardial Infarction by Promoting Scar Formation and Angiogenesis

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CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarction

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Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction

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AMP activated protein kinase 2 protection during hypertension-induced hypertrophy: a common mediator in the signaling crossroads

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Aliskiren and valsartan mediate left ventricular remodeling post-myocardial infarction in mice through MMP-9 effects

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Numerical modeling of ferrous-ion oxidation rate in Acidithiobacillus ferrooxidans ATCC 23270: optimization of culture conditions through statistically designed experiments

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The Mouse Heart Attack Research Tool 1.0 database

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Prevalence of diabetes mellitus and correlation of urinary transforming growth factor-beta1 with blood hemoglobin A1C in the Atascosa Diabetes Study

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Matrix metalloproteinase-9 deletion attenuates myocardial fibrosis and diastolic dysfunction in ageing mice

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Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism

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The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage

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The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor

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Cyclin-dependent kinase 1-dependent phosphorylation of cAMP response element-binding protein decreases chromatin occupancy

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Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies

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Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia

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Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage

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ATR activation necessary but not sufficient for p53 induction and apoptosis in hydroxyurea-hypersensitive myeloid leukemia cells

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Cathepsin L secretion by host and neoplastic cells potentiates invasion

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Stromal cells in breast cancer as a potential therapeutic target

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Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers

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Zinc finger E-box binding homeobox-1 (Zeb1) drives anterograde lysosome trafficking and tumor cell invasion via upregulation of Na+/H+ Exchanger-1 (NHE1)

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The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo

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Correction: A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion

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A Novel High Content Imaging-Based Screen Identifies the Anti-Helminthic Niclosamide as an Inhibitor of Lysosome Anterograde Trafficking and Prostate Cancer Cell Invasion

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Proteomic analysis identifies in vivo candidate matrix metalloproteinase-9 substrates in the left ventricle post-myocardial infarction

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Immunology & Virology

Lymphocytes upregulate CD36 in adipose tissue and liver

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Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade A Envelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants

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Anti-HIV IgM protects against mucosal SHIV transmission

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Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques

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Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge

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Antibody-mediated immune exclusion of HIV

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Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge

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Multimodality vaccination against clade C SHIV: partial protection against mucosal challenges with a heterologous tier 2 virus

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Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose

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Live-virus exposure of vaccine-protected macaques alters the anti-HIV-1 antibody repertoire in the absence of viremia

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Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission

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Novel biopanning strategy to identify epitopes associated with vaccine protection

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No acquisition: a new ambition for HIV vaccine development?

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High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia

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Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection

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Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges

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An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV

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A live attenuated Listeria monocytogenes vaccine vector expressing SIV Gag is safe and immunogenic in macaques and can be administered repeatedly

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Development of a tier 1 R5 clade C simian-human immunodeficiency virus as a tool to test neutralizing antibody-based immunoprophylaxis

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R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models

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Bimodal AIDS vaccine approach: induction of cellular as well as humoral immunity can protect from systemic infection

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HIV infection in India: epidemiology, molecular epidemiology and pathogenesis

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Evidence of a novel B/C recombinant exhibiting unique breakpoints of near full-length HIV type 1 genome from Northeastern India

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Characterization of B/C recombinants of near full-length HIV type 1 from northeastern India with mosaics identical to ARE195FL but with a different ancestral origin

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Quantitation of HLA proteins incorporated by human immunodeficiency virus type 1 and assessment of neutralizing activity of anti-HLA antibodies

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Extensive cross-reactive neutralizing antibody response in Indian patients with limited genetic diversity of HIV-1

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Cytolytic T lymphocytes (CTLs) from HIV-1 subtype C-infected Indian patients recognize CTL epitopes from a conserved immunodominant region of HIV-1 Gag and Nef

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Dysregulation of proinflammatory and regulatory cytokines in HIV infected persons with active tuberculosis

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Consistent subtype-specific anti-HIV type 1 T lymphocyte responses in Indian subjects recently infected with HIV type 1

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Epstein-Barr virus stably confers an invasive phenotype to epithelial cells through reprogramming of the WNT pathway

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Identification of small molecules that disrupt vacuolar function in the pathogen Candida albicans

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